1131 - Assessment of Liver Iron by R2-MRI data analysis

Page last updated: 13 July 2016

Application Detail



Description of Medical Service

This application is for a service that uses measurements from MRI images to calculate iron concentration in the liver.
The majority of transfusion dependent patients have thalassaemia major, a genetic disorder characterised by defective haemoglobin production. Sufferers require regular blood transfusions, and consequently receive excess iron which accumulates causing irreversible tissue damage. The service is designed to optimise iron chelating therapy, a treatment used to remove excess iron from the body, by providing accurate liver iron measurements to determine optimal chelation dose.
The service uses data collected from a standard MRI scanner that are then electronically transferred to a central, offsite, facility for analysis and report (No MRI image is required). The software application is intended to be used in-house as a measuring device, and does not come into direct contact with patients.
The service is indicated for individuals with, or suspected of, systemic iron overload where:
  • a definitive diagnosis of iron overload is required; or
  • monitoring of the liver iron burden is required for ongoing clinical management.

Description of Medical Condition


Reason for Application


Medical Service Type


Previous Application Number

Not Applicable

Associated Documentation

Application Form


PICO Confirmation


Assessment Report

Assessment Report (PDF 1672 KB)
Assessment Report (Word 2119 KB)

Public Summary Document

Public Summary Document (PDF 45 KB)
Public Summary Document (Word 46 KB)

MSAC One Page Summary (PDF 127 KB)
MSAC One Page Summary (Word 29 KB)

Meetings for this Application






29 - 30 July 2010