Australian Government - Department of Health

Medical Services Advisory Committee (MSAC)

1161 - Gefitinib first line testing for mutations of epidermal growth factor receptor (EGFR) in patients with metastatic non-small cell lung cancer

The documents published on this page may not be accessible. If you need assistance please contact the MSAC Secretariat
Application Number1161
Application NameGefitinib first line testing for mutations of epidermal growth factor receptor (EGFR) in patients with metastatic non-small cell lung cancer (NSCLC)
Description of Medical ServiceThis application seeks to extend availability of a test already funded on the MBS for use of gefitinib for first-line treatment in patients with locally advanced or metastatic NSCLC.
Description of Medical ConditionThere are three histological defined subgroups of NSCLC: (i) adenocarcinoma – often found in an outer area of the lung; (ii) squamous cell carcinoma – usually found in the centre of the lung by an air tube (bronchus); and (iii) large cell carcinoma – may occur in any part of the lung which tends to grow and spread faster than the other two types.

Regardless of the subgroup, NSCLC arises as a consequence of either acquired (somatic) and/or inherited (germ-line) mutations.
Protocols14-15 September 2011
PDF version Consultation Decision Analytic Protocol (PDF 1431 KB)
Word version Consultation Decision Analytic Protocol (Word 704 KB)

PDF version Final Decision Analytic Protocol (DAP) (PDF 394 KB)
Word version Final Decision Analytic Protocol (DAP) (Word 747 KB)
ConsultationConsultation Protocol released for comment 25 July 2011 and closed for comment 18 August 2011
Reports-
MSAC OutcomesPDF version Public Summary Document - November 2012 (PDF 927 KB)
Word version Public Summary Document - November 2012 (Word 329 KB)

PDF version Public Summary Document - August 2013 (PDF 129 KB)
Word version Public Summary Document - August 2013 (Word 99 KB)

Meetings for this Application

Meeting TypeDate
PASC7 July 2011
14 and 15 September 2011
ESC 11 and 12 October 2012
MSAC 29 and 30 November 2012
1 August 2013

Page currency, Latest update: 05 November, 2014