Australian Government - Department of Health

Medical Services Advisory Committee (MSAC)

1221 - Transurethral Injection of Botulinum Toxin into the Bladder Wall for Urinary Incontinence due to Neurogenic Detrusor Overactivity

Assessment No

1221
Application NameTransurethral Injection of Botulinum Toxin into the Bladder Wall for Urinary Incontinence due to Neurogenic Detrusor Overactivity
Assessment TypeSubmission Based Assessment
Description Of Medical ServiceThe patient may be given a local anaesthetic with or without sedation, or general anaesthesia, prior to the procedure. A rigid or flexible cystoscope is inserted through the urethra and into the bladder to allow visualisation of the bladder wall. Reconstituted Botox® (200U in 30ml) is then injected into the inner muscular layer of the bladder wall.
Description Of Medical ConditionUrinary incontinence due to neurogenic overactive bladder (NOAB) also called neurogenic detrusor overactivity (NDO) is a distinct subset of the overactive bladder (OAB) syndrome that arises either as a direct result of a primary neurologic disorder (such as multiple sclerosis) or spinal cord injury or secondary to a non-neurologic disease impacting the bladder’s neural pathway.
Pre Assessment Meeting16 August 2011
Stage 2 - Suitability for Assessment6 September 2011
Lodgement of Proposed DAP31 August 2011
Stage 3 - 1st PASC 1-2 December 2011
Stage 3 – Release for Public CommentDate of released for comment 27 January 2012
PDF version Consultation Decision Analytical Protocol (DAP) (PDF 251 KB)
Word version Consultation Decision Analytic Protocol (DAP) (Word 340 KB)
Date of closed for comments 10 March 2012
Stage 3 - 2nd PASC12-13 April 2012
PDF version Final Decision Analytic Protocol ( DAP) (PDF 1351 KB)
Word version Final Decision Analytic Protocol (DAP) (Word 184 KB)
Assessment TypeSubmission Based Received 14 June 2012
Stage 4 - Submission of Collated EvidenceReceived 14 June 2012
Submission withheld at the request of the Applicant
Stage 5 - ESC evaluation11-12 October 2012
Stage 6 - MSAC Appraisal29-30 November 2012
Stage 6 - MSAC advicePDF version Public Summary Document (PDF 835 KB)
Word version Public Summary Document (Word 347 KB)


Re-Submission

Assessment No1221
Assessment TypeRe-submission
Stage 6 - MSAC Appraisal5 April 2013
Stage 6 - MSAC advicePDF version Final Public Summary Document (PDF 93 KB)
Word version Final Public Summary Document (Word 681 KB)

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