1353 - Measurement of Calprotectin as a marker of bowel inflammation

Page last updated: 16 June 2016

Application Detail



Description of Medical Service

Faecal calprotectin is a marker for intestinal inflammation. Calprotectin concentration in faeces correlates with the severity of inflammation and is significantly increased in patients with bowel inflammation (IBD), but not elevated in patients with functional disorders like functional bowel disease (IBS). As a screening tool, faecal calprotectin tests reduce the need for invasive diagnostic procedures (such as colonoscopy), potentially leading to earlier diagnosis of IBD and IBS and subsequently improving patient management.

Description of Medical Condition

Patients present to a doctor with gastrointestinal symptoms suggestive of either organic (IBD) or functional (IBS) bowel disease, namely: chronic abdominal pain and discomfort; urgency and bloating; diarrhea; constipation; alternating bouts of diarrhea and constipation; and changes in bowel habits in the absence of alarm symptoms such as rectal bleeding or abnormal blood tests.

Reason for Application

New MBS item

Medical Service Type


Previous Application Number

Not Applicable

Associated Documentation

Application Form


PICO Confirmation

Comment on the Draft protocol closed at 11:59 on 14 November 2014
Unratified Draft Protocol for Consultation (PDF 354 KB)
Unratified Draft Protocol for Consultation (Word 569 KB)

Feedback and Survey Form (PDF 44 KB)
Feedback and Survey Form (Word 71 KB)

Assessment Report


Public Summary Document


Meetings for this Application


14 - 15 August 2014