1732 – Imlifidase as a desensitisation treatment to enable kidney transplant in highly sensitised adult transplant candidates

Page last updated: 13 October 2023

Application Detail

Description of Medical Service

Imlifidase is a treatment used to prevent the body from rejecting a newly transplanted kidney. It is used before transplantation in people who have antibodies against the donor kidney and are considered ’highly sensitised’ based on a positive crossmatch test. It is a desensitisation treatment, used to convert people from crossmatch positive, to negative and therefore reducing the likelihood of the recipient's body rejecting the donated kidney.

Description of Medical Condition

End-stage kidney disease is defined by partial or completely failed kidney function. Patients require regular dialysis or a kidney transplant for survival.

Reason for Application

Highly Specialised Therapy- National Health Reform Agreement

Medical Service Type

Therapeutic technology

Previous Application Number/s

Not Applicable

Associated Documentation

Application Form

Application Form (PDF 2033 KB)
Application Form (Word 1634 KB)

Consultation Survey

Consultation Survey (PDF 658 KB)
Consultation Survey (Word 27 KB)

PASC Consultation
PASC consultation closed

MSAC Consultation
MSAC consultation input closed Friday, 9 June 2023.

For further information please refer to PASC, ESC, MSAC Key Dates
For further information on the consultation process please refer to MSAC Consultation Process

PICO Confirmation

PICO Confirmation (PDF 1890 KB)
PICO Confirmation (Word 1104 KB)

Assessment Report


Public Summary Document

Public Summary Document (PDF 827 KB)
Public Summary Document (Word 302 KB)

Meetings for this Application


8–9 December 2022


8-9 June 2023


27-28 July 2023