Australian Government - Department of Health and Ageing

Medical Services Advisory Committee (MSAC)

Reference 06

Intracytoplasmic sperm injection (ICSI)

Reference No.

Ref 06

Reference NameIntracytoplasmic sperm injection (ICSI)
Advisory PanelsProfessor Peter Phelan
(Chair and MSAC member)
Associate Professor Gordon Baker
(co-opted member)
Mr Colin Dowell
(Consumers' Health Forum of Australia nominee)
Dr David Golovsky
(Urological Society of Australasia nominee)
Dr Anne Jequier
(Fertility Society of Australia nominee)
Date Received by MSAC Secretariat18 August 1999
Stage 1 - EligibilityEligible
Stage 2 - AssessmentCompleted
Stage 3 - Formulation of Advice to the MinisterThe Minister endorsed the ICSI recommendations from the March 2005 meeting following the public release of The Assisted Reproductive Technology report November 2006 which confirmed MSAC's recommendations.

The report of the Independent Review of Assisted Reproductive Technologies (ART Report) was publicly released in November 2006. The ART Report's findings support the MSAC's ICSI recommendations from March 2005. The Minister has now endorsed the MSAC's recommendations on ICSI.

Part 1: Surgical retrieval of sperm for intracytoplasmic sperm injection

MSAC recommended that on the strength of evidence pertaining to surgical retrieval of sperm for intracytoplasmic sperm injection, public funding should be supported for percutaneous needle aspiration and open (surgical) biopsy procedures for the surgical retrieval of sperm, and intracytoplasmic sperm injection using surgically retrived sperm for men with azoospermia (obstructive or non-obstructive), severe oligospermia, anejaculation not responsive to electroejaculation or vibrostimulation, radical prostatectomy, complete teratozoospermia, complete necrozoospermia or complete sperm immotility.

Part 2: Intracytoplasmic sperm injection using ejaculated sperm

MSAC recommended that, on the strength of the evidence pertaining to the safety, effectiveness and cost effectiveness of intracytoplasmic sperm injection using ejaculated sperm, public funding should be supported for use of this procedure in couples with male factor infertility, under the following circumstances:

When there are severe semen abnormalities and fertilisation with standard IVF is highly unlikely to be successful; and

When a previous cycle of IVF has failed.
Stage 4 - DecisionEndorsed by the Minister for Health and Ageing on 5 February 2007
Stage 5 - ImplementationImplemented
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