Australian Government - Department of Health

Medical Services Advisory Committee (MSAC)

1174 - Pathology test to determine if a patient has been infected with CCR5 tropic HIV-1 for access to maraviroc

Application Number

Application NamePathology test to determine if a patient has been infected with CCR5 tropic Human Immunodeficiency Virus Type 1 (HIV-1) for access to maraviroc
Description of Medical ServiceA proposal was received seeking genotypic HIV tropism testing to be funded through two avenues: (1) through the creation of a new MBS item number to allow HIV tropism testing as part of the current genotype-assisted antiretroviral resistance testing suite of tests; and (2) through the creation of a new MBS item number for HIV tropism testing alone.

HIV tropism testing is a co-dependent technology to determine eligibility for access to maraviroc.
Description of Medical ConditionHIV is a viral infection that causes immunosuppression. If untreated this leads to a number of different opportunistic infections and diseases that are called Acquired Immune Deficiency Syndrome (AIDS). AIDS diseases are often life-threatening and prior to the introduction of effective antiretroviral therapies, patients with AIDS had a prognosis of around two years. The treatment of HIV-1 is complex, with the choice to treat and choice of treatment highly individualised. Treatment decisions depend on virologic efficacy, drug-drug interaction potential, resistance testing results, and co-morbid conditions.
Consultation Protocol14 October 2011 to 11 November 2011
PDF Version Consultation Protocol (PDF 132 KB)
Word Version Consultation Protocol (Word 362 KB)
Final ProtocolPDF version Final Decision Analytic Protocol (DAP) (PDF 137 KB)
Word version Final Decision Analytic Protocol (DAP) (Word 390 KB)
ReportsThe Submission has been withheld at the request of the Applicant
MSAC OutcomesPDF version Public Summary Document (PDF 739 KB)
Word version Public Summary Document (Word 357 KB)

Meetings for this Application
Meeting Type:Date:
PASC14 - 15 September 2011, 1 - 2 December 2011
ESC 11 - 12 October 2012
MSAC 29 - 30 November 2012

Page currency, Latest update: 05 November, 2014