Application Detail
Description of Medical Service
Ciltacabtagene autoleucel (cilta-cel) is a chimeric antigen receptor T (CAR-T) cell therapy for treatment of patients with multiple myeloma (MM) who are refractory or have failed more than three lines of prior therapy. The therapy involves taking the patient’s own cells from peripheral blood, enriching them for T-cells (a type of white blood cell that is an essential part of the immune system) and genetically modifying them before infusing them back into the patient to treat the MM.Description of Medical Condition
Multiple Myeloma (MM) is a cancer affecting a type of white blood cell, known as a plasma cell. Plasma cells are found in the bone marrow and make up a part of the immune system. When cancerous, they accumulate to a point where there is not enough space left for normal, healthy blood cells to be produced. MM can cause bone disease, kidney problems, anaemia, increased risk of infection and blood-clotting.Reason for Application
Highly Specialised Therapy- National Health Reform AgreementMedical Service Type
Therapeutic technologyPrevious Application Number/s
Not ApplicableAssociated Documentation
Application Form
Application Form (PDF 1422 KB)Application Form (Word 604 KB)
Consultation Survey
Consultation Survey (PDF 690 KB)Consultation Survey (Word 72 KB)
PASC Consultation
PASC consultation closed
MSAC Consultation
MSAC consultation input must be received by no later than Friday, 10 June 2022 for it to be considered by MSAC at its July 2022 meeting.
For further information please refer to PASC, ESC, MSAC Key Dates
For further information on the consultation process please refer to MSAC Consultation Process
PICO Confirmation
PICO Confirmation (PDF 1408 KB)PICO Confirmation (Word 1348 KB)